Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904167 | 0.83 | ST14 (0.44) | ST14CSNK2A1TAAR5TAAR1 | |
| SCHEMBL12239033 | 0.80 | SCN9A (0.42) | ST14FFAR1 | |
| SCHEMBL12239019 | 0.79 | ST14 (0.52) | ST14TAAR1 | |
| SCHEMBL13904121 | 0.78 | ROCK2 (0.49) | ST14CSNK2A1TAAR5TAAR1OPRK1 | |
| SCHEMBL12239029 | 0.75 | ST14 (0.50) | ST14FFAR1TAAR1TTR | |
| SCHEMBL12239036 | 0.75 | ST14 (0.50) | ST14TAAR1 | |
| SCHEMBL7677443 | 0.73 | ABAT (0.48) | TAAR1 | |
| SCHEMBL7372727 | 0.73 | ABAT (0.48) | TAAR1 | |
| SCHEMBL2778066 | 0.73 | ABAT (0.48) | TAAR1 | |
| SCHEMBL15192487 | 0.72 | ALDH1A1 (0.50) | UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |