Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 9/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169718 | 0.89 | RAB9A (0.43) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6740354 | 0.79 | ITGB1 (0.42) | PDCD1CD274SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6740346 | 0.79 | ITGB1 (0.42) | PDCD1CD274SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12502286 | 0.75 | NPC1 (0.63) | SMN1; SMN2LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL8181958 | 0.73 | ITGB1 (0.54) | — | |
| SCHEMBL5236788 | 0.70 | HCAR3 (0.61) | PDCD1CD274SMN1; SMN2LMNANPC1 | |
| SCHEMBL31586440 | 0.70 | HCAR3 (0.61) | PDCD1CD274SMN1; SMN2LMNANPC1 | |
| SCHEMBL5233593 | 0.70 | SMN1; SMN2 (0.53) | PDCD1CD274SMN1; SMN2LMNANPC1 | |
| SCHEMBL2734222 | 0.70 | EPHX2 (0.51) | SMN1; SMN2LMNAALDH1A1HTTNPSR1 | |
| SCHEMBL21117877 | 0.70 | EPHX2 (0.51) | SMN1; SMN2LMNAALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369229-B1 | IMMUNOLOGY AND ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS, LIMITED (GB) | 2002-04-09 | — | — | US | disclosed |