Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.66 |
| ▸ | HTR2C | P28335 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7658449 | 0.84 | HTR2B (0.66) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7655748 | 0.84 | HCRTR1 (0.70) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| SCHEMBL7659058 | 0.82 | HTR2B (0.64) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7657543 | 0.82 | HTR2C (0.64) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| SCHEMBL7661474 | 0.82 | HTR2B (0.64) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| SCHEMBL7457165 | 0.80 | HTR2C (1.00) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7661483 | 0.79 | HTR2C (0.97) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| SCHEMBL7101667 | 0.76 | HTR2C (0.72) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL5964738 | 0.75 | HTR2C (0.70) | HTR2BHTR2CRAB9AMAPTKMT2A | |
| SCHEMBL5964118 | 0.73 | HTR2B (0.74) | HTR2BHTR2CRAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | claimed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |