Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.64 |
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656800 | 0.82 | HTR2B (0.66) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| Hydrochloric Acid SCHEMBL7655748 | 0.82 | HCRTR1 (0.70) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| Hydrochloric Acid SCHEMBL7658449 | 0.82 | HTR2B (0.66) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| SCHEMBL7661474 | 0.80 | HTR2B (0.64) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| Hydrochloric Acid SCHEMBL7657543 | 0.80 | HTR2C (0.64) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| SCHEMBL7457165 | 0.78 | HTR2C (1.00) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| Hydrochloric Acid SCHEMBL7661483 | 0.77 | HTR2C (0.97) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| SCHEMBL7101667 | 0.75 | HTR2C (0.72) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| SCHEMBL3101355 | 0.74 | HCRTR1 (1.00) | HTR2BHTR2CHCRTR1HCRTR2RAB9A | |
| SCHEMBL38660785 | 0.74 | HCRTR1 (1.00) | HTR2BHTR2CHCRTR1HCRTR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | claimed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |