Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815478 | 0.88 | MAPT (0.77) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7656920 | 0.86 | MAPT (0.56) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL7589800 | 0.82 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7569736 | 0.81 | MAPT (0.62) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6814660 | 0.79 | MAPT (0.62) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL7645910 | 0.78 | MAPT (0.80) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6816087 | 0.78 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7568740 | 0.78 | MAPT (0.58) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6815173 | 0.78 | MAPT (0.60) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL7656912 | 0.77 | KMT2A (0.48) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |