Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656906 | 0.86 | MAPT (0.66) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6815484 | 0.85 | MAPT (0.71) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6815187 | 0.80 | MAPT (0.66) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7589807 | 0.80 | ALDH1A1 (0.56) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7569745 | 0.79 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6814667 | 0.77 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7645918 | 0.76 | LMNA (0.86) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6816091 | 0.76 | LMNA (0.56) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7568750 | 0.76 | MAPT (0.58) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7686274 | 0.75 | MAPT (0.69) | MAPTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |