Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656913 | 1.00 | NR4A1 (0.49) | NR4A1NR4A2NR4A3LTB4RLTB4R2 | |
| SCHEMBL7656926 | 1.00 | NR4A1 (0.49) | NR4A1NR4A2NR4A3LTB4RLTB4R2 | |
| SCHEMBL6655419 | 0.81 | CA1 (0.59) | NR4A1NR4A2NR4A3MAPT | |
| SCHEMBL6655426 | 0.81 | CA1 (0.59) | NR4A1NR4A2NR4A3MAPT | |
| SCHEMBL6655424 | 0.81 | CA1 (0.59) | NR4A1NR4A2NR4A3MAPT | |
| Hydrochloric Acid SCHEMBL9445571 | 0.80 | CA1 (0.57) | NR4A1NR4A2NR4A3MAPT | |
| SCHEMBL15991117 | 0.79 | L3MBTL1 (0.53) | NR4A1NR4A2NR4A3LTB4RLTB4R2 | |
| SCHEMBL8123793 | 0.79 | CA1 (0.61) | NR4A1NR4A2NR4A3RAB9APOLB | |
| SCHEMBL155030 | 0.79 | CA1 (0.61) | NR4A1NR4A2NR4A3RAB9APOLB | |
| SCHEMBL657699 | 0.79 | L3MBTL1 (0.66) | L3MBTL1MAPTGAARAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413995-B1 | IMMUNOMODULATORS | TSUMURA & CO. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1142875-A1 | CINNAMAMIDE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | TSUMURA & CO. (JP) | 2001-10-10 | — | — | EP | disclosed |