Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237075 | 0.85 | NAAA (0.49) | ALDH1A1OPRD1ABCB1NAAAPPARA | |
| SCHEMBL291952 | 0.85 | NAAA (0.49) | ALDH1A1OPRD1ABCB1NAAAPPARA | |
| SCHEMBL237076 | 0.85 | NAAA (0.49) | ALDH1A1OPRD1ABCB1NAAAPPARA | |
| SCHEMBL6244705 | 0.84 | NAAA (0.48) | ALDH1A1OPRD1NAAAPPARAPPARG | |
| SCHEMBL7652786 | 0.78 | IL6ST (0.41) | ALDH1A1ABCB1PPARAPPARGLTB4R | |
| SCHEMBL7655411 | 0.78 | PPARA (0.40) | ALDH1A1ABCB1PPARAPPARG | |
| SCHEMBL291359 | 0.75 | NAAA (0.57) | ALDH1A1NAAAPPARAPPARG | |
| SCHEMBL3690352 | 0.75 | NAAA (0.57) | ALDH1A1NAAAPPARAPPARG | |
| SCHEMBL291360 | 0.75 | NAAA (0.57) | ALDH1A1NAAAPPARAPPARG | |
| SCHEMBL9683998 | 0.75 | NAAA (0.41) | ALDH1A1NAAAPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448409-B1 | ACYLATION OF AN 2-OXAZOLIDINESELONE WITH AN ALKYL ACYLHALIDE AND HYDROXYLATION WITH AN ALDEHYDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-10 | — | — | US | disclosed |