Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.78 |
| ▸ | DRD3 | P35462 | 7/20 | 0.78 |
| ▸ | DRD4 | P21917 | 6/20 | 0.78 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.78 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.78 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.78 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.78 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.78 |
| ▸ | HTR1A | P08908 | 6/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | DRD5 | P21918 | 1/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6860289 | 0.98 | DRD2 (0.76) | DRD2DRD3DRD4ADRB2CHRM2 | |
| Hydrochloric Acid SCHEMBL7831963 | 0.85 | DRD2 (0.62) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL7041798 | 0.85 | GRIN1 (0.71) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL5988317 | 0.85 | KCNH2 (0.88) | DRD2DRD3CHRM4CHRM3HTR1A | |
| SCHEMBL6867106 | 0.84 | DRD2 (0.78) | DRD2DRD3DRD4KCNH2 | |
| SCHEMBL9030433 | 0.84 | HTR1A (0.74) | DRD2DRD3DRD4ADRB2CHRM2 | |
| Hydrochloric Acid SCHEMBL6867233 | 0.84 | GRIN1 (0.70) | DRD2DRD3DRD4ADRB2CHRM2 | |
| Hydrochloric Acid SCHEMBL7653425 | 0.83 | DRD2 (0.77) | DRD2DRD3DRD4KCNH2 | |
| SCHEMBL7986148 | 0.83 | HTR1A (1.00) | ADRA1DADRA1AADRA1BHTR1AHTR7 | |
| SCHEMBL7620067 | 0.83 | CHRM2 (0.80) | DRD2DRD3DRD4ADRB2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083950-A | TREATMENT OF PERIPHERAL VASCULAR DISEASE, CONGESTIVE HEART FAILURE, HYPERTENSION AND ESPECIALLY BENIGN PROSTATIC HYPERTROPHY | RANBAXY LABORATORIES LIMITED (IN) | 2000-07-04 | — | — | US | claimed |
| US-6420366-B1 | PERIPHERAL VASCULAR DISEASE, CONGESTIVE HEART FAILURE, HYPERTENSION AND ESPECIALLY BENIGN PROSTATIC HYPERTROPHY. | RANBAXY LABORATORIES LIMITED (IN) | 2002-07-16 | — | — | US | disclosed |