Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789416 | 0.98 | LMNA (0.97) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL1819794 | 0.98 | LMNA (0.97) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| Hydrochloric Acid SCHEMBL5606289 | 0.97 | LMNA (1.00) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL1427926 | 0.90 | LMNA (0.81) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL6663882 | 0.87 | KMT2A (0.73) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL10862008 | 0.86 | KMT2A (0.71) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL20481400 | 0.86 | LMNA (0.71) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL3624300 | 0.86 | KMT2A (0.71) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL6640308 | 0.86 | LMNA (0.71) | LMNAALDH1A1KMT2AMEN1OPRM1 | |
| SCHEMBL1242029 | 0.86 | ALDH1A1 (0.71) | LMNAALDH1A1KMT2AMEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1033366-A2 | Amide derivatives useful as Neuropeptide Y (NPY) antagonists | Pfizer Products Inc. (US) | 2000-09-06 | — | — | EP | disclosed |