SCHEMBL765745

SCHEMBL765745

CN1CC(C(=O)c2ccnn2CC2=CCC(F)C=C2)=C(O)C1=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 19/20 0.34
LIPC P11150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751967 0.77 LIPG (0.48) LIPGLIPC
SCHEMBL755691 0.64 NPSR1 (0.41) LIPG
SCHEMBL752105 0.59 LIPG (0.50) LIPGLIPC
SCHEMBL753666 0.57 LIPG (0.47) LIPGLIPC
SCHEMBL752899 0.56 LIPG (0.51) LIPGLIPC
SCHEMBL751203 0.55 LIPG (0.50) LIPGLIPC
SCHEMBL2778238 0.55 LIPG (0.47) LIPGLIPC
SCHEMBL6078188 0.55 LIPG (0.49) LIPGLIPC
SCHEMBL14724756 0.55
SCHEMBL13618586 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1422218-B1 ANTIVIRAL AGENT SHIONOGI & CO (JP) 2012-03-21 EP disclosed