SCHEMBL751967

SCHEMBL751967

CN1CC(C(=O)c2ccnn2Cc2ccc(F)cc2)=C(O)C1=O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 16/20 0.48
LIPC P11150 1/20 0.43
MITF O75030 1/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NR3C2 P08235 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755691 0.86 NPSR1 (0.41) LIPGMITFPKMHTTRAB9A
SCHEMBL752105 0.80 LIPG (0.50) LIPGLIPCNPSR1
SCHEMBL753666 0.77 LIPG (0.47) LIPGLIPCHTT
SCHEMBL765745 0.77 LIPG (0.34) LIPGLIPC
SCHEMBL751973 0.76 NPSR1 (0.50) MITFPKMHTTRAB9ANPSR1
SCHEMBL27606176 0.74 NPSR1 (0.48) MITFPKMHTTRAB9ANPSR1
SCHEMBL752899 0.74 LIPG (0.51) LIPGLIPC
SCHEMBL754205 0.72 LIPG (0.47) LIPGLIPC
SCHEMBL751203 0.72 LIPG (0.50) LIPGLIPCRAB9ANPSR1
SCHEMBL2778238 0.72 LIPG (0.47) LIPGLIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070277-A Androgen receptor PROTAC 葛兰素史密斯克莱知识产权发展有限公司 2026-05-19 CN claimed
EP-4121421-B1 BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS NOVARTIS AG (CH) 2026-03-11 EP claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP claimed
US-12410174-B1 Small molecular inhibitors of sting signaling compositions and methods of use TYERELL IMMUNOTHERAPEUTICS INC (US) 2025-09-09 US claimed
CN-120049017-A Org/ZnSO4Electrolyte, preparation method thereof and application of electrolyte in secondary battery 同济大学 2025-05-27 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-115298170-B Biaryl derivatives as YAP/TAZ-TEAD protein-protein interaction inhibitors 诺华股份有限公司 2024-09-27 CN claimed
CN-118696036-A PARP1 inhibitors 突触活化疗法股份有限公司 2024-09-24 CN claimed
CN-118507836-B Electrolyte for secondary lithium metal battery 深圳欣界能源科技有限公司 2024-09-17 CN claimed
WO-2002012242-A2 BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PHARMACIA ITALIA S.P.A. (IT) 2002-02-14 WO claimed
CN-1284165-A Method and reagents for quantification of solid-phase reactions using fluorine NMR AVENTISS PHARMACEUTICAL PRODUC (US) 2001-02-14 CN claimed
EP-1044364-A1 METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR Aventis Pharmaceuticals Products Inc. (US) 2000-10-18 EP claimed
WO-1999031491-A1 METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-06-24 WO claimed
US-5874444-A CONTROLLING CELL AGING GERON CORPORATION (US) 1999-02-23 US claimed
EP-0696270-B1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RES CAMPAIGN TECH (GB) 1998-11-04 EP claimed
US-5811454-A 3-FLUOROBENZAMIDES WITH NITROGEN MUSTARD GROUPS; ANTICARCINOGENIC AGENTS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-09-22 US claimed
JP-H08509490-A 1996-10-08 JP claimed
EP-0696270-A1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1996-02-14 EP claimed
WO-1994025429-A1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1994-11-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410174-B1 Small molecular inhibitors of sting signaling compositions and methods of use STING1, IRF3, MAVS LIPG 1425/4885LIPC 2706/4885MITF 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.