Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 12/20 | 0.59 |
| ▸ | CTSL | P07711 | 12/20 | 0.59 |
| ▸ | CTSS | P25774 | 11/20 | 0.59 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657500 | 1.00 | CTSB (0.59) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL6737538 | 0.86 | CTSB (0.64) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL6737537 | 0.86 | CTSB (0.64) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL7660389 | 0.84 | CTSL (0.67) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL7660394 | 0.84 | CTSL (0.67) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL6740630 | 0.84 | CTSL (0.69) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6740626 | 0.84 | CTSL (0.69) | CTSBCTSLCTSSCTSK | |
| SCHEMBL7663176 | 0.84 | CTSL (0.61) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL7663178 | 0.84 | CTSL (0.61) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL7663280 | 0.82 | CTSL (0.67) | CTSBCTSLCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |