Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200398 | 0.82 | VCAM1 (0.50) | KHKVCAM1GRIA1GRIA2GRIA3 | |
| SCHEMBL456768 | 0.78 | ALDH1A1 (0.44) | VCAM1MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL3369289 | 0.75 | KHK (0.69) | KHKCYP2C9HPGDTDP1ALDH1A1 | |
| SCHEMBL29755422 | 0.75 | KHK (0.69) | KHKCYP2C9HPGDTDP1ALDH1A1 | |
| SCHEMBL23234456 | 0.75 | ALDH1A1 (0.44) | VCAM1MAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL3790793 | 0.75 | ALDH1A1 (0.39) | VCAM1MAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL2975188 | 0.75 | CYP3A4 (0.44) | MAPTHPGDTDP1ALDH1A1HTT | |
| SCHEMBL13019612 | 0.75 | ALDH1A1 (0.39) | VCAM1MAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL30987771 | 0.75 | ALDH1A1 (0.44) | VCAM1MAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL30987781 | 0.75 | CYP3A4 (0.44) | MAPTHPGDTDP1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489344-B1 | FOR TREATMENT DIABETES IN A HUMAN OR ANIMAL SUBJECT | CHIRON CORPORATION | 2002-12-03 | — | — | US | disclosed |