Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695026 | 0.94 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL20695025 | 0.93 | ALDH1A1 (0.57) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL30984114 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL7658905 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL7664206 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL25698987 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL23812434 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL20707625 | 0.82 | FFAR1 (0.47) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL7660561 | 0.80 | RAB9A (0.57) | ALDH1A1TDP1RAB9ALMNANPC1 | |
| SCHEMBL20710378 | 0.79 | HDAC1 (0.51) | LMNASMN1; SMN2TSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |