Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362116 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6356523 | 0.93 | THRA (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6356994 | 0.93 | THRA (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6359174 | 0.92 | MEN1 (0.41) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6359176 | 0.92 | MEN1 (0.41) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6359207 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6362871 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6355462 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6353468 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL6357946 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486342-B1 | Substituted chiral allosteric hemoglobin modifiers | VIRGINIA COMMONWEALTH UNIVERSITY | 2002-11-26 | — | — | US | disclosed |