Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661245 | 0.84 | MEN1 (0.57) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL7657974 | 0.83 | KMT2A (0.68) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6814960 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL7687310 | 0.81 | SMN1; SMN2 (0.60) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6814781 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6811000 | 0.80 | ALDH1A1 (0.63) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6816565 | 0.80 | MAPT (0.60) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6811910 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6816004 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL6815568 | 0.79 | ALDH1A1 (0.69) | MEN1KMT2ANPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |