Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687308 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL7946630 | 0.82 | MAPT (0.58) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL7657979 | 0.81 | MEN1 (0.70) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6814960 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6814781 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6811000 | 0.76 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6816565 | 0.76 | MAPT (0.60) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL7661245 | 0.76 | MEN1 (0.57) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6811910 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6816004 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410571-B1 | VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-25 | — | — | US | disclosed |