Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660027 | 0.92 | NQO1 (0.46) | ALDH1A1KDM4EMAPTNQO1KMT2A | |
| SCHEMBL7666098 | 0.85 | MAPT (0.58) | ALDH1A1HPGDKDM4EMAPTNQO1 | |
| SCHEMBL7656081 | 0.85 | MAPT (0.48) | ALDH1A1KDM4EMAPTNQO1KMT2A | |
| SCHEMBL925724 | 0.81 | MAPT (0.41) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL7651988 | 0.81 | KDM4E (0.41) | ALDH1A1HPGDKDM4EMAPTNQO1 | |
| SCHEMBL7655744 | 0.81 | NMUR2 (0.44) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL7660104 | 0.80 | ADORA3 (0.48) | ALDH1A1HPGDKDM4EMAPTNQO1 | |
| SCHEMBL7654424 | 0.80 | KDM4E (0.54) | ALDH1A1HPGDKDM4EMAPTNQO1 | |
| SCHEMBL7658384 | 0.80 | CSNK2A2 (0.49) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL926119 | 0.78 | KDM4E (0.40) | ALDH1A1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |