Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656081 | 0.84 | MAPT (0.48) | CSNK2A2CSNK2BCSNK2A1CYP1A2CYP1B1 | |
| SCHEMBL7663645 | 0.82 | CYP1B1 (0.36) | CSNK2A2CSNK2BCSNK2A1CSNK2A3CYP1A1 | |
| SCHEMBL7657984 | 0.80 | ALDH1A1 (0.40) | CSNK2A2CSNK2BCSNK2A1CYP1B1MEN1 | |
| SCHEMBL925724 | 0.78 | MAPT (0.41) | CSNK2A2CSNK2BCSNK2A1CYP1A2CYP1B1 | |
| SCHEMBL7660027 | 0.77 | NQO1 (0.46) | CSNK2A2CSNK2BCSNK2A1CYP1A1CYP1A2 | |
| SCHEMBL7661015 | 0.77 | MAOA (0.43) | CYP1A1CYP1A2CYP1B1MEN1MAPT | |
| SCHEMBL7651988 | 0.76 | KDM4E (0.41) | CYP1A2CYP1B1MEN1MAPTKMT2A | |
| SCHEMBL7655744 | 0.76 | NMUR2 (0.44) | CSNK2A2CSNK2BCSNK2A1CYP1A2CYP1B1 | |
| SCHEMBL7666098 | 0.76 | MAPT (0.58) | CSNK2A2CSNK2BCSNK2A1CYP1A2CYP1B1 | |
| SCHEMBL7655719 | 0.75 | MAOA (0.44) | CYP1A1CYP1A2CYP1B1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | disclosed |