SCHEMBL765799

SCHEMBL765799

CCC1CCC(c2ccc(-c3cc(F)c(F)c(F)c3)cc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
ESR2 Q92731 7/20 0.37
ESR1 P03372 6/20 0.37
CYP2C9 P11712 4/20 0.37
CYP3A4 P08684 3/20 0.37
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
DGAT1 O75907 3/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SOAT1 P35610 2/20 0.34
CYP2D6 P10635 1/20 0.33
TRPV3 Q8NET8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378001 1.00 ALDH1A1 (0.39) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8025924 0.96 ALDH1A1 (0.36) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8025925 0.96 ALDH1A1 (0.36) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8025922 0.96 ALDH1A1 (0.36) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL19446498 0.91 ESR2 (0.37) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL18468300 0.90 CYP3A4 (0.39) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL21626057 0.90 ALDH1A1 (0.35) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL13369630 0.89 ALDH1A1 (0.38) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL17552977 0.88 CYP3A4 (0.38) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL21626051 0.88 CYP2C9 (0.50) ALDH1A1ESR2ESR1CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-11053441-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-07-06 US disclosed
EP-3450523-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2021-01-06 EP disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200123443-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-04-23 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
EP-3239273-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DAINIPPON INK & CHEMICALS (JP) 2019-11-13 EP disclosed
US-10465114-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2019-11-05 US disclosed
EP-2098583-A2 Optically isotropic liquid crystal medium and optical device Chisso Corporation (JP) 2009-09-09 EP disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed
US-5958290-A ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-09-28 US disclosed
EP-0452460-B2 ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM MERCK PATENT GMBH (DE) 1999-08-11 EP disclosed
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
US-5344587-A Nitriles MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-09-06 US disclosed
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed
EP-0387032-A1 Trifluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1990-09-12 EP disclosed