SCHEMBL8025924

SCHEMBL8025924

CCC1CCC(C2CCC(c3ccc(-c4cc(F)c(F)c(F)c4)cc3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
ESR2 Q92731 7/20 0.34
ESR1 P03372 6/20 0.34
CYP2C9 P11712 3/20 0.34
CYP3A4 P08684 2/20 0.34
DGAT1 O75907 3/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
SOAT1 P35610 2/20 0.32
CTSC P53634 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CYP2D6 P10635 1/20 0.31
TRPV3 Q8NET8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8025925 1.00 ALDH1A1 (0.36) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8025922 1.00 ALDH1A1 (0.36) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL765799 0.96 ALDH1A1 (0.39) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8378001 0.96 ALDH1A1 (0.39) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL19446498 0.95 ESR2 (0.37) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL19775728 0.90 ALDH1A1 (0.36) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8527865 0.89 CYP2C9 (0.47) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL19546460 0.89 ESR2 (0.39) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8078924 0.89 CYP2C9 (0.47) ALDH1A1ESR2ESR1CYP2C9CYP3A4
SCHEMBL8527858 0.89 CYP2C9 (0.47) ALDH1A1ESR2ESR1CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-11053441-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-07-06 US disclosed
EP-3450523-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2021-01-06 EP disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200123443-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-04-23 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
EP-2808375-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT PRODUCED USING SAME DAINIPPON INK & CHEMICALS (JP) 2020-01-22 EP disclosed
EP-3239273-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DAINIPPON INK & CHEMICALS (JP) 2019-11-13 EP disclosed
US-10457869-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2019-10-29 US disclosed
US-10414979-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-17 US disclosed
US-20140231712-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2014-08-21 US disclosed
US-20140231712-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2014-08-21 US disclosed
US-20120015115-A1 DISPLAY PANEL AU OPTRONICS CORPORATION (TW) 2012-01-19 US disclosed
US-20120015115-A1 DISPLAY PANEL AU OPTRONICS CORPORATION (TW) 2012-01-19 US disclosed
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
EP-0728829-B1 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-05-03 EP disclosed
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0728829-A2 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1996-08-28 EP disclosed
EP-0704512-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-04-03 EP disclosed