Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.53 |
| ▸ | FNTA | P49354 | 7/20 | 0.46 |
| ▸ | FNTB | P49356 | 7/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187666 | 0.91 | CYP11B1 (0.60) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL2789879 | 0.84 | CYP11B1 (0.47) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7194363 | 0.83 | CYP11B1 (0.57) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Bromide SCHEMBL8005944 | 0.82 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6776276 | 0.81 | CYP11B1 (0.57) | CYP11B1CYP11B2 | |
| SCHEMBL7658006 | 0.80 | FNTA (0.47) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7187767 | 0.78 | CYP11B1 (0.60) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL286607 | 0.77 | ALDH1A1 (0.49) | — | |
| SCHEMBL13529261 | 0.77 | CYP11B1 (0.68) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6776413 | 0.76 | CYP11B1 (0.85) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387903-B1 | ANTICANCER AGENT; CARDIOVASCULAR DISORDERS; VIRICIDES | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |