Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658118 | 1.00 | HPGD (0.44) | HPGDLMNAGAAL3MBTL1TP53 | |
| SCHEMBL3459377 | 0.86 | CA12 (0.36) | HPGDLMNAL3MBTL1TP53CYP2C9 | |
| SCHEMBL7459526 | 0.86 | ALDH1A1 (0.39) | HPGDLMNACYP2C9HIF1ACA12 | |
| SCHEMBL7457939 | 0.86 | CA12 (0.36) | HPGDLMNAL3MBTL1NPC1CYP2C9 | |
| SCHEMBL5998853 | 0.86 | CA12 (0.36) | HPGDLMNAL3MBTL1TP53CYP2C9 | |
| SCHEMBL5080478 | 0.86 | ALDH1A1 (0.39) | HPGDLMNACYP2C9HIF1ACA12 | |
| SCHEMBL7658957 | 0.86 | HPGD (0.46) | HPGDLMNAGAAL3MBTL1TP53 | |
| SCHEMBL5998857 | 0.86 | CA12 (0.36) | HPGDLMNAL3MBTL1TP53CYP2C9 | |
| SCHEMBL7457946 | 0.86 | CA12 (0.36) | HPGDLMNAL3MBTL1NPC1CYP2C9 | |
| SCHEMBL7658965 | 0.86 | HPGD (0.46) | HPGDLMNAGAAL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465457-B1 | CONTROLLING PATHOGENS ON PLANTS OR SEEDS | ZENECA LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| US-5939563-A | FUNGICIDES | ZENECA LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |
| US-5777162-A | Intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1998-07-07 | — | — | US | disclosed |
| EP-0606251-B1 | FUNGICIDES | ZENECA LTD (GB) | 1997-01-08 | — | — | EP | disclosed |
| US-5585513-A | CHEMICAL INTERMEDIATES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0711751-A1 | Process for the preparation of intermediates for oxime ether- or 2-phenyl-3-methyl propenoate-fungicides | ZENECA LIMITED (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |