SCHEMBL5080478

SCHEMBL5080478

COC=C(C(=O)O)c1ccccc1CBr

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.39
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
KDM4E B2RXH2 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C9 P11712 1/20 0.35
HIF1A Q16665 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 2/20 0.33
FOLH1 Q04609 1/20 0.33
AKR1C2 P52895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3459410 1.00 ALDH1A1 (0.39) ALDH1A1LMNACA12CA1CA2
SCHEMBL7459526 1.00 ALDH1A1 (0.39) ALDH1A1LMNACA12CA1CA2
SCHEMBL1263085 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4ESMN1; SMN2HIF1A
SCHEMBL5257837 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4ESMN1; SMN2HIF1A
SCHEMBL29437612 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4ESMN1; SMN2HIF1A
SCHEMBL5257839 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4ESMN1; SMN2HIF1A
SCHEMBL7658118 0.86 HPGD (0.44) ALDH1A1LMNACA12CA1CA2
SCHEMBL7658115 0.86 HPGD (0.44) ALDH1A1LMNACA12CA1CA2
SCHEMBL9490817 0.85 ALDH1A1 (0.37) ALDH1A1LMNACA12CA1CA2
SCHEMBL9490813 0.85 ALDH1A1 (0.37) ALDH1A1LMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11882828-B2 Mosquito vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 US disclosed
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 US disclosed
CN-108530335-B Indole compound and preparation method and application thereof 华南农业大学 2021-08-31 CN disclosed
CN-108558905-B Thiopyran [4,3-b ] indole compound and preparation method and application thereof 华南农业大学 2021-03-12 CN disclosed
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 US disclosed
EP-3302056-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME Syngenta Participations AG (CH) 2018-04-11 EP disclosed
WO-2016193267-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2016-12-08 WO disclosed
EP-2565180-A2 ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Oscotec Inc. (KR) 2013-03-06 EP disclosed
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-7166620-B2 Thiazole derivatives with fungicidal activity ISAGRO RICERCA S.R.L. (IT) 2007-01-23 US disclosed
WO-1993007116-A1 FUNGICIDES ZENECA LIMITED (GB) 1993-04-15 WO disclosed
EP-0532022-A1 Acrylate compound, preparation process thereof and fungicide using the same UBE INDUSTRIES, LTD. (JP) 1993-03-17 EP disclosed
US-5192357-A ACRYLATE FUNGICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1993-03-09 US disclosed
WO-1992018487-A1 SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES ZENECA LIMITED (GB) 1992-10-29 WO disclosed
US-5055471-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-08 US disclosed
US-5021581-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-04 US disclosed
EP-0416746-A2 Fungicides containing an alkoxycarbonylvinyl group or an alkyloxyimino group AGREVO UK LIMITED (GB) 1991-03-13 EP disclosed
EP-0378308-A1 Acrylate fungicides AgrEvo UK Limited (GB) 1990-07-18 EP disclosed
US-4822908-A Substituted acrylates and fungicides containing same BASF AKTIENGESELLSCHAFT (DE) 1989-04-18 US disclosed
EP-0299694-A2 Acrylate fungicides AgrEvo UK Limited (GB) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 ALDH1A1 902/4885LMNA 2239/4885CA12 4686/4885
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 ALDH1A1 902/4885LMNA 2239/4885CA12 4686/4885
US-11882828-B2 Mosquito vector control compositions, methods and products utilizing same DDT, MLEC, MSMO1 ALDH1A1 902/4885LMNA 2239/4885CA12 4686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.