Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.36 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.36 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.36 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.36 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.36 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.36 |
| ▸ | PSMB7 | Q99436 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13166112 | 0.94 | OPRL1 (0.38) | CCR2UBE2MDCUN1D1 | |
| SCHEMBL13165768 | 0.92 | OPRL1 (0.36) | CCR2UBE2MDCUN1D1DDR2 | |
| SCHEMBL765568 | 0.90 | SCN9A (0.37) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL765640 | 0.89 | SCN9A (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL12238930 | 0.88 | EPHX2 (0.41) | CCR2BDKRB1PDE4APDE4BPDE4C | |
| SCHEMBL764451 | 0.87 | BDKRB1 (0.35) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL13904098 | 0.85 | CACNA1B (0.34) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL13165776 | 0.84 | OPRL1 (0.35) | CCR2BDKRB1UBE2MDCUN1D1SCN9A | |
| SCHEMBL764500 | 0.84 | BDKRB1 (0.43) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL13165725 | 0.84 | CARM1 (0.34) | CCR2BDKRB1UBE2MDCUN1D1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |