Serine

Serine

SCHEMBL7658418

N[C@@H](CO)C(=O)O.c1ccc2c(c1)C2

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
SLC1A3 P43003 2/20 0.47
SLC1A2 P43004 2/20 0.47
SLC1A1 P43005 2/20 0.47
KIF11 P52732 6/20 0.43
GRM2 Q14416 1/20 0.43
GRM3 Q14832 1/20 0.43
HDAC8 Q9BY41 2/20 0.42
SLC1A5 Q15758 1/20 0.42
LTA4H P09960 1/20 0.41
KYNU Q16719 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL561331 1.00 ALPI (0.50) ALPIPKMPTGS1XIAPSLC7A5
(D)-Serine SCHEMBL6794292 1.00 ALPI (0.50) ALPIPKMPTGS1XIAPSLC7A5
Serine SCHEMBL8607554 0.89 KIF11 (0.50) ALPIPKMPTGS1XIAPSLC7A5
Serine SCHEMBL8609882 0.85 KIF11 (0.48) ALPIPKMPTGS1XIAPSLC7A5
Homoserine SCHEMBL6051437 0.85 KIF11 (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8618296 0.82 KMT2A (0.48) ALPIPKMPTGS1XIAPSLC7A5
Triphenylene SCHEMBL12506418 0.82 SLC7A5 (0.55) ALPIPKMPTGS1XIAPSLC7A5
Naphthalene SCHEMBL29046325 0.82 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
Biphenyl SCHEMBL26686811 0.82 SLC1A5 (0.59) ALPIPKMPTGS1XIAPSLC7A5
D-Glutamate SCHEMBL561574 0.81 SLC1A3 (0.64) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3810184-A2 METHODS OF TREATING OR INHIBITING ONSET OF HUNTINGTON'S DISEASE University of Rochester (US) 2021-04-28 EP claimed
CN-112654366-A Methods of treating or inhibiting the onset of huntington's disease 罗切斯特大学 2021-04-13 CN claimed
CN-104436208-A Anti-tumor drug microcapsule preparation method CHENGDU LYUKE WOOTION TECHNOLOGY CO LTD 2015-03-25 CN claimed
CN-104415008-A Preparation method of anticancer polymer drug microcapsule CHENGDU LVKE HUATONG TECHNOLOGY CO LTD 2015-03-18 CN claimed
CN-104414999-A Anti-tumor targeted nanometer drug-loaded microcapsule preparation method CHENGDU LVKE HUATONG TECHNOLOGY CO LTD 2015-03-18 CN claimed
CN-104415002-A Preparation method for antineoplastic high-molecular microcapsule CHENGDU LVKE HUATONG TECHNOLOGY CO LTD 2015-03-18 CN claimed
WO-2025080209-A1 A COMPOUND FOR PREPARING LIPID NANOPARTICLES ENCAPSULATING AN AGENT, NANOPARTICLE COMPOSITION COMPRISING SAID COMPOUND AND RELATED METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-04-17 WO disclosed
EP-3810184-A2 METHODS OF TREATING OR INHIBITING ONSET OF HUNTINGTON'S DISEASE University of Rochester (US) 2021-04-28 EP disclosed
CN-112654366-A Methods of treating or inhibiting the onset of huntington's disease 罗切斯特大学 2021-04-13 CN disclosed
CN-111358764-A Anti-tumor high-molecular microcapsule and preparation method thereof 成都吱吖科技有限公司 2020-07-03 CN disclosed
CN-104436208-A Anti-tumor drug microcapsule preparation method CHENGDU LYUKE WOOTION TECHNOLOGY CO LTD 2015-03-25 CN disclosed
CN-104414999-A Anti-tumor targeted nanometer drug-loaded microcapsule preparation method CHENGDU LVKE HUATONG TECHNOLOGY CO LTD 2015-03-18 CN disclosed
CN-104415002-A Preparation method for antineoplastic high-molecular microcapsule CHENGDU LVKE HUATONG TECHNOLOGY CO LTD 2015-03-18 CN disclosed
CN-104415008-A Preparation method of anticancer polymer drug microcapsule CHENGDU LVKE HUATONG TECHNOLOGY CO LTD 2015-03-18 CN disclosed
WO-2013123403-A1 THERANOSTICS PLATFORM AND METHODS OF USE SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-08-22 WO disclosed
US-6403055-B1 CARBOXYLATED POLYAMINE COMPOUND DIBRA S.P.A. (IT) 2002-06-11 US disclosed
EP-0915829-A1 DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY BRACCO S.p.A. (IT) 1999-05-19 EP disclosed
WO-1998005625-A1 DIAGNOSTIC IMAGING CONTRAST AGENT WITH IMPROVED IN-SERUM-RELAXIVITY BRACCO S.P.A. (IT) 1998-02-12 WO disclosed