Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618080 | 0.95 | POLB (0.50) | KMT2ALTA4HPOLBTDP1KIF11 | |
| Homoserine SCHEMBL6051437 | 0.90 | KIF11 (0.49) | KMT2ALTA4HPOLBTDP1KIF11 | |
| D-Glutamate SCHEMBL561574 | 0.86 | SLC1A3 (0.64) | KMT2ALTA4HPOLBTDP1KIF11 | |
| Glutamine SCHEMBL4989095 | 0.85 | KMT2A (0.66) | KMT2ALTA4HPOLBTDP1KIF11 | |
| Glutamine SCHEMBL8630970 | 0.83 | KMT2A (0.63) | KMT2ALTA4HPOLBTDP1KIF11 | |
| Serine SCHEMBL7658418 | 0.82 | ALPI (0.50) | LTA4HKIF11SLC1A3SLC1A2SLC1A1 | |
| Serine SCHEMBL561331 | 0.82 | ALPI (0.50) | LTA4HKIF11SLC1A3SLC1A2SLC1A1 | |
| (D)-Serine SCHEMBL6794292 | 0.82 | ALPI (0.50) | LTA4HKIF11SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL59755 | 0.80 | — | — | |
| SCHEMBL31036022 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710324-A | AMINE CONTAINING COMPOUNDS | MERRELL PHARMACEUTICALS INC. (US) | 1998-01-20 | — | — | US | disclosed |
| US-5318992-A | Administering for the treatment of hypotensive conditions and shock | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0446699-A1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-09-18 | — | — | EP | disclosed |