Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A1 | P60842 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665390 | 0.95 | PLK1 (0.44) | EIF4A1PLK1MCHR1KCNA3TRPV1 | |
| SCHEMBL7666152 | 0.94 | PLK1 (0.46) | EIF4A1PLK1KCNA3TRPV1ADRA2C | |
| SCHEMBL7659349 | 0.90 | NCEH1 (0.40) | EIF4A1MCHR1ROCK1ADRA2CSLC6A4 | |
| SCHEMBL7668448 | 0.83 | CYP1A2 (0.46) | ROCK1ADRA2CHTR2CSLC6A4DRD3 | |
| SCHEMBL3157878 | 0.81 | MPL (0.43) | EIF4A1MCHR1ADORA3PSMB5 | |
| SCHEMBL3157719 | 0.80 | MPL (0.42) | EIF4A1MCHR1ADORA3PSMB5 | |
| SCHEMBL3158592 | 0.80 | MAOB (0.45) | EIF4A1ADORA3 | |
| SCHEMBL3160460 | 0.79 | MPL (0.43) | EIF4A1MCHR1ADORA3PSMB5 | |
| SCHEMBL5686594 | 0.79 | MAOB (0.44) | MCHR1SLC6A2TAAR1 | |
| SCHEMBL7661369 | 0.79 | SKP2 (0.42) | EIF4A1SKP2SLC6A2SLC6A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |