Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665390 | 0.98 | PLK1 (0.44) | PLK1FAAHESR1ADRA2AADORA3 | |
| SCHEMBL7658781 | 0.94 | EIF4A1 (0.43) | PLK1ADORA3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7659349 | 0.88 | NCEH1 (0.40) | SLC6A4LMNAADRA2CHTR2AEIF4A1 | |
| SCHEMBL14687958 | 0.82 | ESR1 (0.48) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL3171568 | 0.82 | RARB (0.43) | PLK1FAAHEIF4A1 | |
| SCHEMBL3166939 | 0.82 | RARB (0.43) | PLK1FAAHEIF4A1 | |
| SCHEMBL3160446 | 0.81 | RARB (0.46) | PLK1FAAHALDH1A1HSD17B10S1PR1 | |
| SCHEMBL3167236 | 0.81 | RARB (0.46) | PLK1FAAHALDH1A1HSD17B10S1PR1 | |
| SCHEMBL3160428 | 0.81 | RARB (0.42) | PLK1FAAHHSD17B10EIF4A1 | |
| SCHEMBL3157854 | 0.81 | RARB (0.42) | PLK1FAAHHSD17B10EIF4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |