Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659349 | 0.86 | NCEH1 (0.40) | KIF11BACE1HTR2AHTR2BROCK1 | |
| SCHEMBL7658781 | 0.83 | EIF4A1 (0.43) | HTR2AHTR2BHTR2CROCK1SIGMAR1 | |
| SCHEMBL7665390 | 0.82 | PLK1 (0.44) | HTR2AHTR2CLMNAADRA2CSLC6A4 | |
| SCHEMBL7666152 | 0.81 | PLK1 (0.46) | HTR2AHTR2CLMNAADRA2CSLC6A4 | |
| SCHEMBL12310186 | 0.80 | BACE1 (0.48) | KIF11BACE1MAPTKDM4E | |
| SCHEMBL12473661 | 0.80 | BACE1 (0.48) | KIF11BACE1MAPTKDM4E | |
| SCHEMBL12320899 | 0.80 | BACE1 (0.48) | KIF11BACE1MAPTKDM4E | |
| SCHEMBL3168004 | 0.79 | PSEN1 (0.42) | CYP1A2CYP2A6KIF11MAPTMAOB | |
| SCHEMBL12317664 | 0.78 | BACE1 (0.47) | KIF11BACE1MAPTKDM4E | |
| SCHEMBL3960187 | 0.78 | PSEN1 (0.41) | CYP1A2CYP2A6KIF11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |