Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 7/20 | 0.54 |
| ▸ | ELANE | P08246 | 17/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499604 | 0.92 | CTRB1 (0.56) | CTRB1ELANEMEN1ALDH1A1KMT2A | |
| SCHEMBL6496779 | 0.86 | CTRB1 (0.56) | CTRB1ELANEMEN1ALDH1A1KMT2A | |
| SCHEMBL7658836 | 0.85 | CTRB1 (0.53) | CTRB1ELANEMEN1ALDH1A1KMT2A | |
| SCHEMBL6500859 | 0.85 | CTRB1 (0.53) | CTRB1ELANEMEN1ALDH1A1KMT2A | |
| SCHEMBL7845338 | 0.84 | ELANE (0.54) | CTRB1ELANEMEN1KMT2A | |
| SCHEMBL6507056 | 0.82 | CTRB1 (0.51) | CTRB1ELANEMEN1ALDH1A1KMT2A | |
| SCHEMBL6496223 | 0.82 | ELANE (0.72) | CTRB1ELANEALDH1A1 | |
| SCHEMBL6498025 | 0.81 | CTRB1 (0.47) | CTRB1ELANEKMT2A | |
| SCHEMBL6504063 | 0.81 | CTRB1 (0.50) | CTRB1ELANEALDH1A1KMT2A | |
| SCHEMBL7839307 | 0.80 | ELANE (0.55) | CTRB1ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380189-B1 | FOR TREATING HERPES-RELATED DISORDERS | G.D. SEARLE & CO. | 2002-04-30 | — | — | US | disclosed |