Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499604 | 0.92 | CTRB1 (0.56) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL7839307 | 0.90 | ELANE (0.55) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL7843279 | 0.88 | ELANE (0.51) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL7837321 | 0.85 | ELANE (0.70) | ELANECTRB1 | |
| SCHEMBL7658844 | 0.84 | CTRB1 (0.54) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL6496779 | 0.84 | CTRB1 (0.56) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL6500859 | 0.80 | CTRB1 (0.53) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL6595086 | 0.80 | ELANE (0.74) | ELANECTRB1 | |
| SCHEMBL27477143 | 0.80 | ELANE (0.74) | ELANECTRB1 | |
| SCHEMBL7658836 | 0.79 | CTRB1 (0.53) | ELANECTRB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | claimed |