Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150038 | 0.92 | KMT2A (0.77) | KMT2ACA1CA2MAPK1SRD5A2 | |
| SCHEMBL503642 | 0.83 | KMT2A (1.00) | KMT2ACA1CA2MAPK1SRD5A2 | |
| SCHEMBL7192855 | 0.83 | KMT2A (0.65) | KMT2ACA1CA2MAPK1SRD5A2 | |
| Aminobenzoic Acid SCHEMBL11151165 | 0.83 | KMT2A (0.65) | KMT2ACA1CA2MAPK1SRD5A2 | |
| SCHEMBL11145345 | 0.82 | KMT2A (0.62) | KMT2ACA1CA2MAPK1SRD5A2 | |
| SCHEMBL79929 | 0.82 | KMT2A (0.74) | KMT2ACA1CA2MAPK1SRD5A2 | |
| Ethane SCHEMBL27686450 | 0.82 | KMT2A (0.96) | KMT2ACA1CA2MAPK1SRD5A2 | |
| SCHEMBL10867743 | 0.82 | KMT2A (0.74) | KMT2ACA1CA2MAPK1SRD5A2 | |
| SCHEMBL10426836 | 0.81 | RXFP1 (0.59) | KMT2ACA1CA2MAPK1PARP10 | |
| SCHEMBL718568 | 0.80 | KMT2A (0.61) | KMT2ACA1CA2MAPK1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | disclosed |
| US-6355633-B1 | CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | FSHR, GNRHR, LHCGR | KMT2A 1116/4885CA1 1385/4885CA2 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.