SCHEMBL718568

SCHEMBL718568

C=COC(C)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.61
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MAPK1 P28482 1/20 0.45
SRD5A2 P31213 3/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PARP10 Q53GL7 2/20 0.42
RXRA P19793 2/20 0.42
RXRB P28702 2/20 0.42
HSD17B10 Q99714 1/20 0.41
MAPT P10636 1/20 0.41
RARB P10826 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
PARP15 Q460N3 1/20 0.40
HTT P42858 1/20 0.39
XDH P47989 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2453171 0.95 KMT2A (0.56) KMT2ACA1CA2MAPK1SRD5A2
SCHEMBL2449694 0.93 KMT2A (0.53) KMT2ACA1CA2MAPK1SRD5A2
SCHEMBL2447821 0.88 KDM4E (0.55) KMT2ACA1CA2MAPK1ALDH1A1
SCHEMBL11966970 0.87 MAPT (0.48) KMT2AALDH1A1L3MBTL1PARP10MAPT
SCHEMBL150038 0.84 KMT2A (0.77) KMT2ACA1CA2MAPK1SRD5A2
SCHEMBL1344967 0.84 ALDH1A3 (0.39) KMT2AALDH1A1L3MBTL1PARP10TP53
SCHEMBL7797255 0.81 KMT2A (0.57) KMT2ACA1CA2MAPK1SRD5A2
SCHEMBL7658930 0.80 KMT2A (0.71) KMT2ACA1CA2MAPK1SRD5A2
SCHEMBL722081 0.80 CA12 (0.49) KMT2ACA1CA2ALDH1A1L3MBTL1
SCHEMBL9193031 0.79 KMT2A (0.65) KMT2ACA1CA2MAPK1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8439495-B2 Ink jet liquid composition, set, liquid cartridge, and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2013-05-14 US disclosed
EP-2423271-B1 Ink jet liquid composition, set, liquid cartridge, and ink jet recording method CANON KK (JP) 2012-12-19 EP disclosed
US-20120050391-A1 INK JET LIQUID COMPOSITION, SET, LIQUID CARTRIDGE, AND INK JET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2012-03-01 US disclosed
EP-2423271-A1 Ink jet liquid composition, set, liquid cartridge, and ink jet recording method Canon Kabushiki Kaisha (JP) 2012-02-29 EP disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120050391-A1 INK JET LIQUID COMPOSITION, SET, LIQUID CARTRIDGE, AND INK JET RECORDING METHOD MITF, KATNAL2, RB1 KMT2A 688/4885CA1 4697/4885CA2 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.