Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615300 | 1.00 | CYP2C9 (0.41) | CYP2C9CYP11B1CYP11B2GPR35MAPT | |
| SCHEMBL9475692 | 0.86 | GPR35 (0.39) | CYP2C9GPR35MAPTKDM4EALDH1A1 | |
| SCHEMBL9475695 | 0.86 | GPR35 (0.39) | CYP2C9GPR35MAPTKDM4EALDH1A1 | |
| SCHEMBL9475701 | 0.86 | GPR35 (0.39) | CYP2C9GPR35MAPTKDM4EALDH1A1 | |
| SCHEMBL7486003 | 0.84 | CYP2C9 (0.43) | CYP2C9CYP11B1CYP11B2MAPTKDM4E | |
| SCHEMBL7654922 | 0.84 | CYP2C9 (0.43) | CYP2C9CYP11B1CYP11B2MAPTKDM4E | |
| SCHEMBL9562415 | 0.80 | CYP2C9 (0.40) | CYP2C9CYP11B1CYP11B2GPR35MAPT | |
| SCHEMBL9212344 | 0.80 | CYP2C9 (0.40) | CYP2C9CYP11B1CYP11B2GPR35MAPT | |
| SCHEMBL5704344 | 0.80 | GPR35 (0.37) | CYP2C9GPR35MAPTKDM4EALDH1A1 | |
| SCHEMBL5704342 | 0.80 | GPR35 (0.37) | CYP2C9GPR35MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432948-B1 | ANTIULCER AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-13 | — | — | US | disclosed |
| US-6133260-A | Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for the treatment of Helicobacter pylori infections and associated gastroduodenal diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |