Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592732 | 0.83 | PTPN1 (0.35) | PTPN1 | |
| SCHEMBL7198006 | 0.80 | PTPN1 (0.42) | PTPN1 | |
| SCHEMBL7663140 | 0.79 | PTPN1 (0.44) | PTPN1 | |
| SCHEMBL7594291 | 0.77 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL7659257 | 0.76 | PTPN1 (0.56) | PTPN1 | |
| SCHEMBL7193789 | 0.75 | MCHR1 (0.32) | — | |
| SCHEMBL7596319 | 0.74 | EPHX1 (0.35) | — | |
| SCHEMBL7659254 | 0.74 | PTPN1 (0.57) | PTPN1 | |
| SCHEMBL7695855 | 0.74 | PTPN1 (0.32) | PTPN1AKR1B1 | |
| SCHEMBL7595806 | 0.74 | PTPN1 (0.39) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498151-B2 | PROTEIN TYROSINE PHOSPHATASES INHIBITORS, ESPECIALLY AS ANTIDIABETIC AGENTS | MERCK FROSST CANADA & CO. (CA) | 2002-12-24 | — | — | US | claimed |