Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.63 |
| ▸ | F10 | P00742 | 11/20 | 0.63 |
| ▸ | F7 | P08709 | 4/20 | 0.63 |
| ▸ | F3 | P13726 | 4/20 | 0.63 |
| ▸ | PLAU | P00749 | 9/20 | 0.59 |
| ▸ | PLAT | P00750 | 9/20 | 0.59 |
| ▸ | PLG | P00747 | 6/20 | 0.58 |
| ▸ | KLK1 | P06870 | 4/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659296 | 0.95 | F2 (0.63) | F2F10F7F3PLAU | |
| SCHEMBL12046470 | 0.85 | ALDH1A1 (0.66) | DHODHSMO | |
| SCHEMBL7656504 | 0.83 | PLAU (0.53) | F2F10F7F3PLAU | |
| SCHEMBL6851324 | 0.82 | KMT2A (0.56) | DHODHSMO | |
| SCHEMBL7657141 | 0.81 | PLAU (0.53) | F2F10F7F3PLAU | |
| SCHEMBL6852760 | 0.79 | ALDH1A1 (0.53) | DHODH | |
| SCHEMBL6848464 | 0.79 | ALDH1A1 (0.53) | DHODH | |
| SCHEMBL23080512 | 0.79 | ALDH1A1 (0.71) | DHODHSMO | |
| SCHEMBL12046468 | 0.79 | ALDH1A1 (0.66) | DHODHSMO | |
| SCHEMBL7661930 | 0.79 | CYP3A4 (0.69) | F2F10F7F3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | claimed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | claimed |
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |