SCHEMBL6848464

SCHEMBL6848464

O=C(O)c1ccc(NC(=O)c2ccc(-c3ccc(C(=O)O)c(C(=O)O)c3)cc2C(=O)Nc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
GFER P55789 1/20 0.50
CYP1A2 P05177 2/20 0.49
IKBKE Q14164 1/20 0.49
TBK1 Q9UHD2 1/20 0.49
HPGD P15428 1/20 0.49
KDM4E B2RXH2 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MITF O75030 1/20 0.49
FFAR1 O14842 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 1/20 0.47
DHODH Q02127 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852760 1.00 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AGFERCYP1A2
SCHEMBL6851324 0.97 KMT2A (0.56) ALDH1A1MEN1KMT2AGFERIKBKE
SCHEMBL6855624 0.91 HPSE (0.59) ALDH1A1MEN1KMT2ACYP1A2HPGD
SCHEMBL6852794 0.88 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AGFERCYP1A2
SCHEMBL6848412 0.88 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AGFERCYP1A2
SCHEMBL6852426 0.87 PTPN1 (0.58) ALDH1A1MEN1KMT2AGFERIKBKE
SCHEMBL6853182 0.87 PTPN1 (0.58) ALDH1A1MEN1KMT2AGFERIKBKE
SCHEMBL6852782 0.87 HPSE (0.62) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL23080512 0.87 ALDH1A1 (0.71) ALDH1A1MEN1KMT2AGFERCYP1A2
SCHEMBL8900345 0.87 KMT2A (0.59) ALDH1A1MEN1KMT2AGFERCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828408-B2 Small coefficient of linear expansion and small water absorbing property, and excellent heat resistance; thermotropic liquid crystalline polymer for engineering plastics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-07 US disclosed
US-20030083459-A1 Aromatic polyimide ester and method for producing thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-01 US disclosed