Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.63 |
| ▸ | CTSS | P25774 | 10/20 | 0.63 |
| ▸ | CTSB | P07858 | 10/20 | 0.63 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659354 | 1.00 | CTSL (0.63) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL4716574 | 0.89 | CTSL (0.64) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL7663280 | 0.89 | CTSL (0.67) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL7663286 | 0.89 | CTSL (0.67) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL7661873 | 0.88 | CTSL (0.66) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL7661866 | 0.88 | CTSL (0.66) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL7668380 | 0.87 | CTSB (0.67) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL7668373 | 0.87 | CTSB (0.67) | CTSLCTSSCTSBCTSKCTSV | |
| SCHEMBL6740630 | 0.87 | CTSL (0.69) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6740626 | 0.87 | CTSL (0.69) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |