Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662876 | 0.95 | CA12 (0.37) | CA12CA1CA2CA9KDR | |
| SCHEMBL7665490 | 0.90 | ACKR3 (0.33) | CA12CA1CA2CA9KDR | |
| SCHEMBL7663434 | 0.89 | TP53 (0.38) | TP53USP2POLBMAPT | |
| SCHEMBL7657220 | 0.86 | CAMK2D (0.42) | KDR | |
| SCHEMBL7662310 | 0.85 | IDO1 (0.36) | CA12CA1CA2CA9KDR | |
| Acetic Acid SCHEMBL7657913 | 0.85 | PDE4A (0.42) | CA12CA1CA2CA9KDR | |
| SCHEMBL7658124 | 0.84 | CA12 (0.38) | CA12CA1CA2CA9KDR | |
| Acetic Acid SCHEMBL7659539 | 0.82 | MKNK1 (0.41) | CA12CA1CA2CA9KDR | |
| Acetic Acid SCHEMBL7658112 | 0.82 | PDE4A (0.41) | CA12CA1CA2CA9KDR | |
| Acetic Acid SCHEMBL7807324 | 0.82 | IDO1 (0.43) | CA12CA1CA2CA9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |