SCHEMBL7659660

SCHEMBL7659660

NCCOC(=O)/C=C/c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 7/20 0.69
AKR1B1 P15121 7/20 0.69
LMNA P02545 3/20 0.63
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
MAOB P27338 1/20 0.57
ALDH1A1 P00352 3/20 0.57
APP P05067 2/20 0.57
CA12 O43570 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
RAB9A P51151 1/20 0.51
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
ALOX15 P16050 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19511647 1.00 AKR1B10 (0.69) AKR1B10AKR1B1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7174329 0.98 AKR1B10 (0.67) AKR1B10AKR1B1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL7174326 0.98 AKR1B10 (0.67) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL8007281 0.91 AKR1B10 (0.66) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL8007828 0.91 AKR1B10 (0.66) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL144598 0.90 AKR1B10 (0.65) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL144597 0.90 AKR1B10 (0.65) AKR1B10AKR1B1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL29992270 0.89 AKR1B10 (0.64) AKR1B10AKR1B1LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL28536906 0.89 AKR1B10 (0.64) AKR1B10AKR1B1LMNAMEN1KMT2A
SCHEMBL19279512 0.89 AKR1B10 (0.83) AKR1B10AKR1B1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121265-B Intelligent release targeted migration type reinforcement corrosion inhibitor 江苏苏博特新材料股份有限公司 2022-11-22 CN claimed
US-20210380727-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2021-12-09 US claimed
CN-113121265-A Intelligent release targeted migration type reinforcement corrosion inhibitor 江苏苏博特新材料股份有限公司 2021-07-16 CN claimed
EP-3760647-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE Mochida Pharmaceutical Co., Ltd. (JP) 2021-01-06 EP claimed
CN-111918881-A Novel photocrosslinkable alginic acid derivative 持田制药株式会社 2020-11-10 CN claimed
US-11779593-B2 Agent for improving ocular subjective symptoms and method thereof SEIKAGAKU CORPORATION (JP) 2023-10-10 US disclosed
CN-113121265-B Intelligent release targeted migration type reinforcement corrosion inhibitor 江苏苏博特新材料股份有限公司 2022-11-22 CN disclosed
US-11472891-B2 Photocrosslinkable alginic acid derivative MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed
CN-111918881-B Novel photocrosslinkable alginic acid derivative 持田制药株式会社 2022-08-12 CN disclosed
CN-114848515-A Flawless cosmetic emulsion and preparation method thereof 安婕妤化妆品科技股份有限公司 2022-08-05 CN disclosed
US-20220105125-A1 AGENT FOR IMPROVING OCULAR SUBJECTIVE SYMPTOMS AND METHOD THEREOF SEIKAGAKU CORPORATION (JP) 2022-04-07 US disclosed
US-20210380727-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2021-12-09 US disclosed
WO-1997041104-A1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-06 WO disclosed
WO-1997028153-A1 CHINOLINE AND BENZIMIDAZOLE DERIVATIVES AS BRADYKININ AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-08-07 WO disclosed
EP-0774462-A1 HETEROCYCLIC COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-21 EP disclosed
WO-1997011069-A1 HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-27 WO disclosed
US-5574042-A ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN FUJISAWA PHARMACEUTICAL CO., LTD (JP) 1996-11-12 US disclosed
US-5563162-A CAN BE ADMINISTERD FOR THE TREATMENT OF ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASES, SHOCK OR PAIN IN ANIMALS AND HUMANS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-10-08 US disclosed
EP-0622361-A1 Heterocyclic compounds as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-02 EP disclosed
EP-0596406-A1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-11 EP disclosed