SCHEMBL8007281

SCHEMBL8007281

NCCOCCOC(=O)C=Cc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 7/20 0.66
AKR1B1 P15121 7/20 0.66
LMNA P02545 2/20 0.56
MAOB P27338 1/20 0.56
APP P05067 2/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 2/20 0.49
ALOX15 P16050 2/20 0.49
ALOX12 P18054 2/20 0.49
MAPK1 P28482 2/20 0.49
HSD17B10 Q99714 2/20 0.49
RAB9A P51151 2/20 0.49
TTR P02766 2/20 0.49
ALOX5 P09917 2/20 0.49
KDM4E B2RXH2 1/20 0.49
GMNN O75496 1/20 0.49
EGFR P00533 1/20 0.49
ESR1 P03372 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8007828 1.00 AKR1B10 (0.66) AKR1B10AKR1B1LMNAMAOBAPP
Hydrochloric Acid SCHEMBL28536906 0.98 AKR1B10 (0.64) AKR1B10AKR1B1LMNAMAOBAPP
Hydrochloric Acid SCHEMBL29992270 0.98 AKR1B10 (0.64) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL18393355 0.92 AKR1B10 (0.76) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL15929684 0.92 AKR1B10 (0.76) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL18404759 0.92 AKR1B10 (0.76) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL7659660 0.91 AKR1B10 (0.69) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL19511647 0.91 AKR1B10 (0.69) AKR1B10AKR1B1LMNAMAOBAPP
SCHEMBL28529970 0.90 AKR1B10 (0.54) AKR1B10AKR1B1LMNAMAOBAPP
Hydrochloric Acid SCHEMBL7174326 0.89 AKR1B10 (0.67) AKR1B10AKR1B1LMNAMAOBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210380727-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2021-12-09 US claimed
EP-3760647-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE Mochida Pharmaceutical Co., Ltd. (JP) 2021-01-06 EP claimed
US-11472891-B2 Photocrosslinkable alginic acid derivative MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed
US-20210380727-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2021-12-09 US disclosed
EP-3760647-A1 NOVEL PHOTOCROSSLINKABLE ALGINIC ACID DERIVATIVE Mochida Pharmaceutical Co., Ltd. (JP) 2021-01-06 EP disclosed
EP-0713859-B1 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO CO LTD (JP) 2000-08-30 EP disclosed
US-6107410-A Cinnamic acid derivative SEIKAGAKU CORPORATION (JP) 2000-08-22 US disclosed
US-6025444-A HYALURONIC ACID POLYSACCHARIDE DERIVATIVE; PHOTODIMERIZABLE, CROSSLINKABLE SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 2000-02-15 US disclosed
EP-0713859-A2 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1996-05-29 EP disclosed