Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997931 | 1.00 | FFAR1 (0.50) | FFAR1KDM1AGPR88EPHX2FFAR4 | |
| SCHEMBL23425328 | 1.00 | FFAR1 (0.50) | FFAR1KDM1AGPR88EPHX2FFAR4 | |
| SCHEMBL21501071 | 1.00 | FFAR1 (0.50) | FFAR1KDM1AGPR88EPHX2FFAR4 | |
| SCHEMBL18984237 | 1.00 | FFAR1 (0.50) | FFAR1KDM1AGPR88EPHX2FFAR4 | |
| SCHEMBL27699503 | 0.86 | GPR88 (0.43) | FFAR1KDM1AGPR88EPHX2MAOB | |
| SCHEMBL18559979 | 0.84 | FFAR1 (0.51) | FFAR1KDM1ACYP4F2CYP4A11 | |
| SCHEMBL18559754 | 0.84 | FFAR1 (0.51) | FFAR1KDM1ACYP4F2CYP4A11 | |
| SCHEMBL22721277 | 0.82 | GPR88 (0.48) | FFAR1KDM1AGPR88EPHX2FFAR4 | |
| SCHEMBL28947449 | 0.80 | IDO1 (0.54) | FFAR1EPHX2FFAR4CYP4F2CYP4A11 | |
| SCHEMBL16030266 | 0.80 | FFAR1 (0.40) | FFAR1KDM1AGPR88FFAR4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369064-B1 | MYOCARDIAL INFARCTION AND UNSTABLE ANGINA; P2T-RECEPTOR ANTAGONISTS; ANTITHROMBOTIC AGENTS; 7-(SUBSTITUTED AMINO) -5-(THIO)-3H-1,2,3-TRIAZOLO(4,5-D)PYRIMIDIN-3-YL) -CYCLOPENTANECARBOXAMIDES | ASTRAZENECA AB (SE) | 2002-04-09 | — | — | US | disclosed |