Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721277 | 0.96 | GPR88 (0.48) | GPR88SLC9A1EPHX2KDM1AMAOB | |
| SCHEMBL18984237 | 0.86 | FFAR1 (0.50) | GPR88EPHX2KDM1AMAOBFFAR1 | |
| SCHEMBL21501071 | 0.86 | FFAR1 (0.50) | GPR88EPHX2KDM1AMAOBFFAR1 | |
| SCHEMBL6997931 | 0.86 | FFAR1 (0.50) | GPR88EPHX2KDM1AMAOBFFAR1 | |
| SCHEMBL7659702 | 0.86 | FFAR1 (0.50) | GPR88EPHX2KDM1AMAOBFFAR1 | |
| SCHEMBL23425328 | 0.86 | FFAR1 (0.50) | GPR88EPHX2KDM1AMAOBFFAR1 | |
| SCHEMBL4608225 | 0.80 | SCN9A (0.44) | GPR88EPHX2KDM1AMAOBL3MBTL1 | |
| SCHEMBL19836055 | 0.79 | GAA (0.38) | EPHX2MAPTL3MBTL1EPHX1FFAR1 | |
| SCHEMBL22398100 | 0.79 | FFAR1 (0.53) | GPR88SLC9A1KDM1AMAOBALDH1A1 | |
| SCHEMBL15542075 | 0.78 | SLC9A1 (0.43) | SLC9A1MAPTL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |