Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 2/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030305 | 0.84 | GPR119 (0.49) | — | |
| SCHEMBL7663579 | 0.76 | GPR119 (0.53) | — | |
| SCHEMBL7663392 | 0.73 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3CACNA1BGBA1 | |
| SCHEMBL3581153 | 0.70 | GRIN2B (0.56) | SLC6A2SLC6A4SLC6A3GBA1CHIA | |
| SCHEMBL16757238 | 0.70 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL989955 | 0.69 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CACNA1BGBA1 | |
| SCHEMBL7657929 | 0.68 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3CACNA1BGBA1 | |
| SCHEMBL27544724 | 0.68 | GRIN2B (0.58) | SLC6A2SLC6A4SLC6A3GBA1 | |
| SCHEMBL990020 | 0.67 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CACNA1B | |
| SCHEMBL16097011 | 0.67 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3GBA1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498161-B1 | TREATING INFECTION BY HIV; DELAYING OF THE ONSET OF AIDS; ASTHMA, ALLERGIC RHINITIS, DERMATITIS, CONJUNCTIVITIS, ATHEROSCLEROSIS OR RHEUMATOID ARTHRITIS | MERCK & CO., INC. | 2002-12-24 | — | — | US | disclosed |
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |