Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891030 | 0.81 | TAAR1 (0.53) | TAAR1IDO1DAOHRH3XIAP | |
| SCHEMBL3590222 | 0.81 | CA1 (0.57) | TAAR1IDO1DAOCA2ALDH1A1 | |
| SCHEMBL1641618 | 0.79 | RECQL (0.58) | RECQLCA2ALDH1A1 | |
| SCHEMBL24505558 | 0.78 | IDO1 (0.53) | TAAR1IDO1 | |
| SCHEMBL12493473 | 0.78 | TAAR1 (0.58) | TAAR1IDO1RECQLCA2 | |
| SCHEMBL4878820 | 0.78 | TAAR1 (0.58) | TAAR1IDO1RECQL | |
| SCHEMBL4881416 | 0.78 | TAAR1 (0.58) | TAAR1IDO1RECQLDAOCA2 | |
| SCHEMBL5117104 | 0.77 | TAAR1 (0.62) | TAAR1IDO1HRH3CA2 | |
| SCHEMBL6453428 | 0.77 | RECQL (0.47) | RECQLDAOCA2ALDH1A1HTR6 | |
| SCHEMBL29596752 | 0.77 | TAAR1 (0.74) | TAAR1IDO1DAOHRH3XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492348-B1 | Adenosine derivatives | SMITHKLINE BEECHAM CORPORATION | 2002-12-10 | — | — | US | disclosed |