Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13181396 | 0.85 | PTGS2 (0.44) | CA2HDAC4HDAC8CA1CA5A | |
| SCHEMBL688510 | 0.83 | BCHE (0.43) | CA2HDAC4HDAC8CA1CA5A | |
| SCHEMBL688319 | 0.82 | BCHE (0.42) | CA2HDAC4HDAC8CA1CA5A | |
| SCHEMBL688318 | 0.82 | CA2 (0.38) | CA2HDAC4HDAC8CA1CA5A | |
| SCHEMBL7659779 | 0.77 | TAAR1 (0.58) | RECQLCA2ALDH1A1DAOHTR6 | |
| SCHEMBL3841734 | 0.77 | TAAR1 (0.57) | CA2HDAC4HDAC8CA1CA5A | |
| SCHEMBL1641618 | 0.75 | RECQL (0.58) | RECQLCA2CA1CA5ACA9 | |
| Hydrochloric Acid SCHEMBL14157281 | 0.75 | TAAR1 (0.55) | RECQLKDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL11797022 | 0.74 | CTSS (0.43) | CA2HDAC4HDAC8CA1CA5A | |
| SCHEMBL11167064 | 0.74 | MAOA (0.50) | ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.P.A. (IT) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080951-A2 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A. (IT) | 2004-09-23 | — | — | WO | disclosed |