SCHEMBL7659823

SCHEMBL7659823

CCOc1ccc2c(c1)CCc1cc(F)ccc1-2

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.47
CYP11B1 P15538 2/20 0.47
CYP11B2 P19099 2/20 0.47
MAOB P27338 3/20 0.46
MAOA P21397 2/20 0.46
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MAPK14 Q16539 8/20 0.43
ESR1 P03372 1/20 0.42
NQO1 P15559 1/20 0.42
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7664743 0.87 SLC2A1 (0.48) MAOBMAOACA1CA2CA7
SCHEMBL7667020 0.87 MAOB (0.49) MAOBMAOAMAPK14MAPTL3MBTL1
SCHEMBL7665005 0.84 THRA (0.50) MAOBMAOAMAPK14MAPTL3MBTL1
SCHEMBL7661551 0.83 THRA (0.52) MAOBMAPK14MAPTL3MBTL1MEN1
SCHEMBL7668461 0.81 MAPK14 (0.57) CYP19A1CYP11B2MAPK14MAPTL3MBTL1
SCHEMBL7664919 0.81 MAOB (0.50) CYP19A1CYP11B1CYP11B2MAOBMAOA
SCHEMBL7668645 0.81 MAOB (0.46) CYP19A1CYP11B1CYP11B2MAOBMAOA
SCHEMBL4895513 0.78 NQO1 (0.52) CYP19A1CYP11B1CYP11B2CA1CA2
SCHEMBL1915443 0.78 MAOB (0.60) MAOBMAOAMAPTL3MBTL1
SCHEMBL10071512 0.76 NQO1 (0.54) CYP19A1CYP11B1CYP11B2NQO1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495220-B2 WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS CLARIANT INTERNATIONAL LTD. (CH) 2002-12-17 US disclosed
US-20010023935-A1 With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers CLARIANT INTERNATIONAL LTD. (CH) 2001-09-27 US disclosed