Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17108416 | 0.88 | MPO (0.59) | CYP1A2CYP2D6MPOBCL2KDM4E | |
| SCHEMBL24502858 | 0.81 | MAPK14 (0.46) | MAPK14CYP1A2CYP2D6MPO | |
| SCHEMBL7659823 | 0.81 | CYP19A1 (0.47) | MAPK14MAPTCYP19A1CYP11B2L3MBTL1 | |
| SCHEMBL15869785 | 0.79 | MPO (0.51) | CYP1A2CYP2D6MPOBCL2KDM4E | |
| SCHEMBL7665423 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP2D6MPOBCL2KDM4E | |
| SCHEMBL7664100 | 0.79 | CYP24A1 (0.59) | MAPK14CYP1A2CYP2D6MPOBCL2 | |
| SCHEMBL3141978 | 0.79 | MPO (0.54) | CYP1A2CYP2D6MPOBCL2KDM4E | |
| SCHEMBL7667020 | 0.78 | MAOB (0.49) | MAPK14MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL7664743 | 0.78 | SLC2A1 (0.48) | MAPK14 | |
| SCHEMBL7284296 | 0.78 | ALDH1A1 (0.55) | MAPK14CYP1A2CYP2D6MPOBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |